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Acute Care Surgery / Surgical Critical Care

Bibliography-J. Jason Hoth, MD

 Journal Articles:

  1.  Hoth JJ, Waters GS, Pennell TC. "Results of Local Excision of Benign and Malignant Rectal Lesions" Am Surg 2000 Dec;66(12):1099-1103
  2.  Hoth JJ, Burch PT, Bullock TK, Cheadle WG, Richardson JD. "Pathogenesis ofPosttraumatic Empyema: The Impact of Pneumonia on Pleural Space Infections" Surg Infect .2003 Spring;4(10):29-35
  3.  Hoth JJ, Franklin GA, Stassen NA, Girard SM, Rodriguez RJ, Rodriguez JL. "Prophylactic Antibiotics Adversely Affect Nosocomial Pneumonia in Trauma Patients" J Trauma. 2003 Aug;55(2):249-254
  4. Scott MJ, Hoth JJ, Gardner SA, Peyton JC, Cheadle WG. "Natural Killer Cell Activation Primes Macrophages to Clear Bacterial Infection. Am Surg 2003 Aug;69(8): 679-686; discussion 686-687.
  5. Franklin GA, Scott MJ, Patel M, Hoth JJ, Peyton JC, Cheadle WG. "A Novel Model of Pneumonia from Intraperitoneal Injection of Bacteria" Am J Surg 2003 Nov.186(5); 493-499.
  6.  Hoth JJ, Scott MJ, Owens RK, Stassen NA, Franklin GA, Cheadle WG, Rodriguez JL. "Trauma Alters Alveolar Effector Cell Apoptosis" Surgery 2003 Oct; 134(4):631-637; discussion 637-638.
  7. Rodriguez JL, Brill JP, Hoth JJ, Stassen NA, Franklin GA, Barbier R, Polk HC Jr. "Tertiary Care Centers: A Strategy for Fiscal Survival" Surgery 2003 Oct;134(4): 684-689; discussion 689-690.
  8.  Hoth JJ, Scott MJ, Bullock TK, Stassen NA, Franklin GA, Richardson JD. "Thoracotomy for Blunt Trauma: Traditional Indications May Not Apply" Am Surg 2003 Dec;69(12):1108-1111.
  9. Stassen NA, Hoth JJ, Scott MJ, Day CS, Lukan JK, Rodriguez JL, Richardson JD. "Laryngotracheal Injuries: Does Injury Mechanism Matter?" Am Surg. 2004 Jun;70(6):522-525.
  10. Scott MJ, Hoth JJ, Stagner MK, Gardner SA, Peyton JC, Cheadle WG. "CD40-CD154 Interactions Between Macrophages Activation and Are Not Interferon Gamma Dependent" Clin Exp Immunol 2004 Sep; 137(3):469-477.
  11. Scott MJ, Cheadle WG, Hoth JJ, Peyton JC, Subbarao K, Shao WH, Haribabu B. "Leukotriene B4 receptor (BLT-1) Modulates Neutrophil Influx into the Peritoneum but not the Lung and Liver During Surgically Induced Bacterial Peritonitis in Mice" Clin Diagn Lab Immunol 2004 Sep:11(5) 936-941.
  12. Scott MJ, Hoth JJ, Gardner SA, Peyton JC, Cheadle WG. "Genetic Background Influences Natural Killer Cell Activation During Bacterial Peritonitis in Mice, and is Interleukin 12 and Interleukin 18 independent" Cytokine. 2004 Nov 7;28(3):124-126.
  13. Hundley JC, Kilgo, PD, Miller PR, Chang MC, Hensberry RA, Meredith JW, Hoth JJ. "Non Helmeted Motorcyclists: A Burden to Society? A Study Using the National Trauma Data Bank". J Trauma 2004 Nov;57(5):944-949.
  14. Martin RS, Kilgo PD, Miller PR, Hoth JJ, Meredith JW, Chang, MC. "Injury Associated Hypothermia:"An Analysis of the 2004 National Trauma Data Bank" SHOCK 2005 Aug;24(2)114-118.
  15. Berry GE, Adams S, Harris MB, Boles CA, McKernan MG, Collinson F, Hoth JJ, Meredith JW,  Chang MC, Miller PR. "Are Plain Radiographs of the Spine Necessary During Evaluation After Blunt Trauma? Accuracy of Screening Torso Computed Tomography in Thoracic/Lumbar Spine Fracture Diagnosis" J Trauma. 2005 Dec;59(6):1410-13; discussion 1413.
  16. Scott MJ, Hoth JJ, Gardner SA, Peyton JC, Cheadle WG. "Interleukin 10 Suppresses Natural Killer Cell but not Natural Killer T Cell Activation During Bacterial Infection. Cytokine. 2006  Jan; 33(2) 79-86.
  17. Miller PR, Johnson JC, Karchmer T, Hoth JJ, Meredith JW, Chang MC. "National Nosocomial Infection Surveillance System: From Benchmark to Bedside in Trauma Patients" J Trauma. 2006 Jan;60(1):98-103.
  18. Miller PR, Partrick MS, Hoth JJ, Meredith JW, Chang MC. "A Practical Application of Practice-Based Learning: Development of an Algorithm for Empiric Antibiotic Coverage in Ventilator Associated Pneumonia" J Trauma. 2006 Apr;60(4); 725-9
  19. Martin RS, Norris PR, Kilgo, PD, Miller PR, Hoth JJ, Meredith JW, Chang MC, Morris JA Jr. "Validation of Stroke Work and Ventricular Arterial Coupling as Markers of Cardiovascular Performance during Resuscitation" J Trauma 2006 May 60 (5)930-4; discussion 934-5.
  20. Stitzel JD, Gayzik FS, Hoth JJ, Mercier J, Gage HD, Morton KA, Duma SM, Payne RM.  "Development of a finite element-based injury metric for pulmonary contusion part I: model development and validation."  Stapp Car Crash J. 2005 Nov; 49:271-289
  21.  Hoth JJ, Stitzel JD, Gayzik FS, Brownlee NA, Miller PR, Yoza BK, McCall CE, Meredith JW, Payne RM. "The Pathogenesis of Pulmonary Contusion: An Open Chest Model in the Rat" J Trauma. 2006 Jul;61(1):32-44; discussion 44-45.
  22. Meredith JW, Hoth JJ. "Thoracic Trauma: When and How to Intervene" Surg Clin North Am. 2007 Feb; 87(1):95-118.
  23. Gayzik FS, Hoth JJ, Stitzel JD. "A Comparative Study of Optimization Techniques for Tuning a Finite Element Model of the Lung to Biomechanical Data." Biomed Sci Instrum. 2007; 43:212-217
  24. Danelson KA, Hoth JJ, Miller PR, Stitzel JD. "A Semi-Automated Approach for Measuring Splenic Injury using Computed Tomography." Biomed Sci Instrum. 2007; 43:13-17
  25.  Hoth JJ, Hudson WP, Brownlee NA, Yoza BK, Hiltbold EM, Meredith JW, McCall CE. "Toll-Like Receptor 2 Participates in the Response to Lung Injury in Murine Model of Pulmonary Contusion"  SHOCK 2007 October; 28(4): 447-452
  26. Miller PR, Chang MC, Hoth JJ, Holmes JH 4th, Meredith JW. "Colonic Resection in the Setting of Damage Control Laparotomy: Is Delayed Anastomosis Safe?" Am Surg. 2007 June; 73(6):606-609.
  27. Martin RS, Smith JS, Hoth JJ, Miller, PM, Meredith JW, Chang, MC.  "Increased Insulin Requirements are Associated with Pneumonia after Severe Injury." J Trauma. 2007 Aug; 63(2):358-364.
  28. Turina M, Hoth JJ, Turpen RM, Scott MJ, Cheadle WG. "Alveolar Interleukin-10 Regulates Neutrophil Apoptosis in Severely Traumatized Patients." J Trauma. 2007 Oct; 63(4):733-39.
  29. Gayzik FS, Hoth JJ, Daly M, Meredith JW, Stitzel JD. "A Finite Element-Based Injury Metric for Pulmonary Contusion: Investigation of Candidate Metrics Through Correlation with Computed Tomography" Stapp Car Crash J. 2007 Oct;51:189-209.
  30.  Hoth JJ, Wells JD, Brownlee NA, Hiltbold EM, Meredith JW, McCall CE, Yoza, BK. Toll-like receptor 4 dependent responses to lung injury in a murine model of pulmonary contusion. Shock. 2008;Jul 24.
  31. Daly M, Miller PR, Carr JJ, Gayzik FS, Hoth JJ, Meredith JW, Stitzel JD. "Traumatic Pulmonary Pathology Measured With Computed Tomography and a Semi-Automated Analytic Method." Clin Imaging. 2008 Sep-Oct;32(5):346-354.
  32. Gayzik FS, Hoth JJ, Stitzel JD. "Quantitative History of Contused Lung Tissue With Comparison to Computed Tomography". Biomed Sci Instrum. 2008;44:225-230.
  33. Gayzik FS, Martin RS, Gabler HC, Hoth JJ, Duma SM, Meredith JW, Stitzel JD. "Characterization of Crash-Induced Thoracic Loading Resulting in Pulmonary Contusion." J Trauma. 2009 Mar;66(3):840-849.
  34.  Hoth JJ, Martin RS, Yoza BK, Wells JD, Meredith JW, McCall CE. Pulmonary Contusion Primes Systemic Innate Immunity Responses. J Trauma 2009 Jul; 67 (1):14-21.
  35. AN Hildreth, MD, T Enniss, MD, RS Martin, MD, PR Miller, MD, D Mitten-Long, RN, BSN, J Gasaway RN, F Ebert, RN, W Butcher, RN, K Browder, MC Chang, MD, JJ Hoth, MD, NT Mowery, MD, JW Meredith, MD.  Surgical ICU Mobility is Increased Following Institution of a Computerized Mobility Order Set and ICU Mobility Protocol: A Prospective Cohort Analysis.  AM Surg; Aug 2010. 76 (8):818-822.    
  36.  Gayzik FS, Hoth JJ, Stitzel JD.  Finite Element-Based Injury Metrics for Pulmonary Contusion Via Concurrent Model Optimization. Biomech Model Mechanobiol. 2011 Jul; 10(4):505-20.
  37.  Gajic O, Dabbagh O, Park PK, Adesanya A, Chang SY, Hou P, Anderson Iii H, Hoth JJ, Mikkelsen ME, Gentile NT, Gong MN, Talmor D, Bajwa E, Watkins TR, Festic E, Yilmaz M, Iscimen R, Kaufman DA, Esper AM, Sadikot R, Douglas I, Sevransky J, Malinchoc M, on behalf of the US Critical Illness and Injury Trials Group: Lung Injury Prevention Study Investigators (USCIITG-LIPS). Early Identification of Patients at Risk of Acute Lung Injury: Evaluation of Lung Injury Prediction Score in a Multicenter Cohort Study. Am J Respir Crit Care Med. 2010 Aug 27; PubMed PMID:20802164.  
  38.  Mowery NT, Dougherty SD, Hildreth AN, Holmes JH 4th, Chang MC, Martin RS, Hoth JJ, Meredith, JW, Miller PR. "Emergency Department Length of Stay is an Independent Predictor of Hospital Mortality in Trauma Activation Patients." J Trauma; June 2011 6(70):1317-1325. 
  39.  Hoth JJ, Wells JD, Hiltbold EM, McCall CE, Yoza BK. "Mechanism of Neutrophil Recruitment to the Lung after Pulmonary Contusion". Shock; 2011 June; 35(6):604-9.  
  40. Becher RD, Hoth JJ, Miller PR, Mowery NT, Chang MC, Meredith JW. "A Critical Assessment of Outcomes in Emergency versus Nonemergency General Surgery Using the American College of Surgeons National Surgical Quality Improvement Program Database." Am Surg; July 2011 7(77):951-959. 
  41.  Gayzik FS, Hoth JJ, Stitzel JD.  "Finite Element-Based Injury Metrics for Pulmonary Contusion Via Concurrent Model Optimization." Biomech Model Mechaniobiol 2011 Jul; 10(4):505-20.  
  42.  Becher RD, Hoth JJ, Neff LP, Rebo, JJ, Martin RS, Miller PR. Multidrug-Resistant Pathogens and Pneumonia: Comparing the Trauma and Surgical Intensive Care Units.  Surg Infect (Larchmt). 2011 Aug;12(4):267-72 
  43.  Danelson KA, Gayzik FS, Stern AR, Hoth JJ, Stitzel JD. "Design, Development, and Analysis of a Surrogate for Pulmonary Injury Prediction" Ann Biomed Eng. 2011 Oct;39(10):2560-7. 
  44. Becher RD, Meredith JW, Chang MC, Hoth JJ, Beard HR, Miller PR. "Creation and Implementation of an Emergency General Surgery Registry Modeled after the National Trauma Data Bank". J Am Coll Surg. February 2012; 214:156-163.
  45. Brzoza-Lews KL, Hoth JJ, Hiltbold EM. Type I Interferon Signaling REgulations the Composition of Inflammatory Infiltrates upon Infection with Listeria Monocytogenes. Cell Immunol. 2012;273(1):41-51.
  46. Hoth JJ, Wells JD, Yoza BK, McCall CE. Innate Immune Response to Pulmonary Contusion: Identification of a Cell Type-Specific Inflammatory Responses. Shock 2012 Apr;37(4):385-91.
  47. Becher RD, Hoth JJ, Miller PR, Meredith JW, Chang MC. Systemic Inflammation Worsesn Outcomes in Emergency General Surgery Patients. J Trauma Acute Care Surg. 2012 May;72(5):1140-9.
  48. Becher RD, Chang MC, Hoth JJ, Kendall JL, Beard HR, Miller PR. Does Acute Physiology and Chronic Health Evaluation II Provide a Valid Metric to Directly Compare Disease Severity in Trauma versus Surgical Intesive Care Unit Patients?  Am Surg. 2012 Nov; 78(11):1261-9.
  49. Weaver AA, Danelson KA, Armstrong EG, Hoth JJ, Stitzel JD. Investigation of Pulmonary Contusion Extent and Its Correlation to Crash, Occupant and Injury Chractersitscs in Motor Vehicle Crashes. Accid Anal Prev. 2012 May 8.
  50. Becher RD, Colonna AL, Enniss TM, Weaver AA, Crane DK, Martin RS, Mowery NT, Miller PR, Stitzel JD, Hoth JJ.  An Innovative Approach to Predict the Development of Adult Respiratory Distress Syndrome in Patients with Blunt Trauma. J Trauma Acute Care Surg. 2012 Nov;73(5):1229-35.
  51. Becher RD, Hoth JJ, Rebo JJ, Kendall JL, MIller PR. Locally Derived versus Guideline-Based Approach to Treatment of Hospital -Acquired Pneumonia in the Trauma Intensive Care Unit. Surg Infect.2012 Dec 13(6):352-9.
  52. Karnatovskaia LV. Lee AS, Gajic O, Festic E; U.S. Critical Illness and Injury Trials Group: Lung Ijury Prevention Study Investigators (USCIITG-LIPS). The Influence of Prehospital Systemic Corticosteroid Use on Development of Acute Respiratory Distress Syndrome and Hospital Outcomes. Crit Care Med. 2013 Jul;41(7):1679-85.

  53. Festic E, Ortiz-Diaz E, Lee A, Li G, Kor DJ, Adebola A, Akca O, Hoth J, Levitt JE, Carter R, ​Gajic O; United States Critical Illness and Injury Trials Group:Lung Injury Prevention Study Investigators (USCIITG-LIPS). Prehospital use of Inhaled Steroids and Incidence of Acute Lung Injury Among Patients at Risk. J Crit Care. 2013 Dec; 28(6):985-91.
  54. Hoth JJ, Wells JD, Jones SE, Yoza BK, McCall CE. Complement Mediates a Primed Inflammatory Response After Traumatic Lung Injury. J Trauma Acute Care Surg. 2014 Mar;76(3):601-609.
  55. Miller PR, Chang, Hoth JJ, Mowery NT, Hildreth AN, Martin RS, Holmes JH, Meredith JW, Requarth JA. Prospective Trial of Angiography and Embolization of All Grade III to V Blunt Splenic Injuries: Nonoperative Management Success Rate is Significantly Improved. J Am Coll Surg. 2014; 218 (4):644-648.
  56. Kor DJ, Ligeneni RK, Gajic O, Park PK, Blum JM, Hou PC, Hoth JJ, Anderson JL 3rd, Bajwa EK, Bartz RR, Adesanya A, Festic E, Gong MN, Carter RE, Talmor DS. Predicting Risk of Postoperative Lung Injury in High-Risk Surgical Patients: A Multi-Center Cohort Study. Anesthesiology. 2014 May; 120(5):1168-1181.
  57. Smith LM, Wells JD, Vachharajani VT, Yoza BK, McCall CE Hoth JJ. SIRT1 Mediates a Primed Response to Immune Challenge After Traumatic Lung Injury. J Trauma Acute Care Surg. 2015 May;78:1034-1038.
  58. Lopez JM, McGonagill PW, Gross JL, Hoth JJ, Chang MC, Parker K, Requarth JA, Miller PR.  Subcapsular Hematoma in Blunt Splenic Injury: A Significant Predictor of Failure of Nonoperative Management. J Trauma Acute Care Surg. 2015 Dec; 79(6) 957-960.
  59. Vachharajani VT, Lui T, Wang X, Hoth JJ, Yoza BK, McCall CE.  Sirtuins Link Inflammation and Metabolism.  J Immunol Res. 2016; 2016:8167273
  60. Kor DJ, Carter RE, Park PK, Festic E, Banner-Goodspeed VM, Hinds R, Talmor D, Gajic O, Ware LB, Gong MN; US Critical Illness and Injury Trials Group: Lung Injury Prevention with Aspiring Study Group (USCIITG: LIPS-A) Effect of Aspirin on Development of ARDS in At-Risk Patients Presenting to the Emergency Department:  The LIPS-A Randomized Clinical Trial. JAMA. 2016 Jun 14;315(22)-2406-14. doi:10.1001/jama.2016.6330.

Online Publications:  

 Hoth JJ.  SCORE:Abdomen-Spleen:Post-Splenectomy Sepsis.

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