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Structural Biology Faculty

Investigators in structural biology study the molecular structures and physical properties of proteins, nucleic acids and their complexes. The tools of molecular biology are used to synthesize proteins in large quantities suitable for physical analysis by X-ray crystallography, mass spectrometry, enzymology, and a variety of biophysical methods such as light scattering and sedimentation.

Rebecca Alexander Understanding protein-nucleic acid interactions at the molecular level. Faculty Profile / Publications / Research Details / Lab Page

Jacquelyn Fetrow Computational analysis of functional sites in proteins; development of methods to model biological networks from experimental time course data; and analysis of molecular dynamics and motion in proteins. Faculty Profile / Fetrow Research Group

Roy Hantgan Molecular mechanisms of blood coagulation and fibrinolysis; conformation of proteins in solution. Faculty Profile & Publications / Lab Page

Tom Hollis X-ray crystallographic studies of DNA repair proteins and Fanconi anemia-associated proteins. Faculty Profile & PublicationsLab Page

Daniel Kim-Shapiro Nitrogen oxide signaling in hemoglobin and other heme proteins in normal physiology, disease and therapeutics using various spectroscopies including EPR, light scattering, and time-resolved absorption. Faculty Profile & Publications / Research Interests

Todd Lowther X-ray crystallographic and biochemical analyses of enzymes that repair the oxidative damage to free and protein-incorporated methionine. Faculty Profile & PublicationsLab Page

Derek Parsonage Enzymology of bacterial enzymes involved in defending against oxidative stress: enzymes that utilize flavin and cysteine residues at the catalytic site. Faculty Profile & Publications /Lab Page

Leslie Poole Mechanistic enzymology of bacterial enzymes involved in protection against oxidative stress; novel roles of catalytic cysteine residues. Faculty Profile & PublicationsLab Page

Quick Reference

Telephone 336-713-7005

Dr. Timothy Howard
Program Director

Dr. Nicholette Allred
Graduate Students Recruiting Director

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