Cryoablation (also known as cryotherapy) is delivered directly into the tumor by a probe that is inserted through the skin using imaging to guide it internally. Cryoablation uses an extremely cold gas to freeze the tumor to kill it; the "ice ball" that is created around the needle grows in size and destroys the frozen tumor cells.

Cryoablation is extremely safe, and most patients are sent home the same day or go home the next day.