The molecular oncology laboratory is part of the Molecular Pathology Laboratories in charge of testing for molecular markers important in many neoplastic conditions. Our current testing menu includes:
- BCR::ABL1 quantitative, p210 major breakpoint
- BCR::ABL1 quantitative, p190 minor breakpoint
- PML::RARA, quantitative, bcr 1 (long) and bcr 3 (short) forms
- BRAF mutational analysis
- EGFR mutational analysis
- KRAS mutational analysis
- NRAS mutational analysis
- Immunoglobulin heavy chain gene rearrangement (B-cell clonality)
- T-cell receptor gamma gene rearrangement (T-cell clonality)
- FLT3 mutation analysis (ITD and TKD mutations)
- Next-Generation Sequencing (NGS) for myeloid neoplasms
- Next-Generation Sequencing (NGS) for solid tumors
- MYD88 Mutational Analysis
All specimens submitted for analysis must be accompanied by a requisition form.
Samples may be submitted in several ways:
- Formalin-fixed paraffin embedded (FFPE) tissues, on either glass slides or block (with H&E slide and specified percent tumor).
- Peripheral blood/ bone marrow samples (should be collected in EDTA only).
- Body fluid samples (require a dedicated sample).
- Tubes that have been opened and samples for obtained for other tests will be considered on a case-by-case basis (at the director's discretion).
If Myeloid Panel Next-Generation Sequencing (NGS) testing is desired, please fill out this form and overnight the sample via FedEx using the specimen collection requirements and address listed.
If molecular testing is desired and an order is not available on EPIC, use this form for ordering the tests above (or below, depending on where you will include the slides). The form should be filled out completely, printed, and brought with the respective sample to the Molecular Oncology Laboratory.
Normal turnaround time is estimated to be 3-5 days depending upon the day the sample is received and the test being performed.
Please contact Dr. Christopher Giauque 336-713-7579 for any related questions.