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Decades of Cancer Excellence


In 2024, Atrium Health Wake Forest Baptist Comprehensive Cancer Center is celebrating 50 years as part of the National Cancer Institute (NCI) Cancer Centers Program.  

Our center has maintained NCI designation since 1974, when we were one of the first to be recognized for expertise and leadership in cancer research, prevention and care. 

Today, we’re among the top 5% of cancer centers nationally. Of the 1,000+ cancer programs in the U.S., just 57 are designated as “Comprehensive” for meeting the NCI’s highest standards. 

Our commitment to excellence impacts more lives than ever before. The innovation and research of Atrium Health Wake Forest Baptist Comprehensive Cancer Center fuels Atrium Health Levine Cancer, the largest cancer program in the Carolinas. 

As we proudly reflect on the tremendous progress of the last half century, we look forward to leading the way to a future without cancer.  


Why Our NCI Designation Matters

 

1

of only 57 NCI-designated Comprehensive Cancer Centers in the U.S.

35,000+

new patients treated annually at Levine Cancer locations

500+

clinical trials are currently available for patients with cancer.

 

28+

Levine Cancer locations throughout the Carolinas

 

Greater outcomes may be achieved when choosing to receive care at an NCI-designated Comprehensive Cancer Center, including long-term survival

 

We have research and programs that focus on giving everyone an equal opportunity to prevent, treat and survive cancer.

 

Dr. Ruben Mesa reflects on the impact of NCI-designated cancer centers like ours.

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Comprehensive Cancer Center researchers in a lab.

Fifty Years of Recognized Expertise in Cancer Research

Atrium Health Wake Forest Baptist Comprehensive Cancer Center celebrates 50 years of NCI designation.
Learn More

Our History

1900s

1902

  • Wake Forest College Medical School founded as a 2-year program at Wake Forest College in Wake Forest, NC

1920s

1923

  • North Carolina Baptist Hospital opened as an 88-bed hospital in Winston-Salem

1930s

1939

  • A $750,000 trust fund was established in Bowman Gray Sr.’s will, pledging to relocate Wake Forest College Medical School to Winston-Salem and expand its program from two years to four

1940s

1941

  • Formal opening of Bowman Gray School of Medicine in Winston-Salem with 75 students

Photo: Graduating class of 1943

1950s

1956

  • Wake Forest University opened in Winston-Salem

1957

  • First in North Carolina to use cobalt to treat cancer patients

Photo: In 1957, North Carolina Baptist Hospital installed a supervoltage cobalt-60 unit, a radiation machine used to treat cancer.

1960s

1967

  • Proposal for Oncology Center, including original summary and case for support, was “hand delivered” to the National Cancer Institute (NCI) by Dr. Charles Spurr and Dr. Isadore Meschan

1968

  • Oncology Research Center (ORC) established by Dr. Spurr, ORC 1968-1982 (passed away 1994)

1969

  • First in the nation to use ultrasound to detect prostate cancer

1970s

1971

  • National Cancer Act signed by President Richard Nixon, major focus on world-class cancer research
  • Radiation oncology training initiated

Photo 1: Dr. George Barrett (C’52) adjusts a new scanning device used for image intensification

 

 

 

Photo 2: Dr. Damon Blake, professor in radiology, teaches five students in this undated photograph

1972

  • Dr. Charles Spurr named director of the Cancer Center

Photo: Dr. Charles Spurr

 

 

1974

  • Received NCI-designated Cancer Center status
 

 

1975

  • Dr. Robert Cooper, professor of hematology/oncology at Bowman Gray School of Medicine, named acting director of the Cancer Center of Wake Forest University

Photo: Dr. Robert Cooper 

1976

  • Piedmont Oncology Association (POA) created by Dr. Spurr, 125 physicians across five states

1978

  • Commission on Cancer accreditation by the American College of Surgeons
  • Former Chair of Neurosurgery Dr. Eben Alexander, was a co-investigator on the first Phase III clinical trial for the treatment of patients with glioblastoma

1980s

1980

  • First Brian Piccolo cancer research fundraising event established in memory of the 26-year-old WFU grad and Chicago Bears football player; 3 signature events (Wake and Shake, Hit the Bricks and Pump It Up) have rasied over $4.5 million to date

    Photo: 1988 Check presentation

1980

  • Cancer Patient Support Program started (part-time program), funded by: 
  • Junior League of Winston-Salem 
  • Hillsdale Fund 
  • ORC 
  • Rufus T. Stedman Fund of Winston-Salem Foundation 
  • Greater Charlotte Foundation 

1981 – 1985

  • NCI funded POA due to growth and number of publications (one of 60 community programs)

1982

  • Dr. Robert Capizzi named director of the Cancer Research Center

Photo: Dr. Robert Capizzi

 

1987

  • POA renamed as the Southeast Cancer Control Consortium

Photo: A Plymouth, NC, family donated $10,000 to support the work being done in the Oncology Research Center at Bowman Gray School of Medicine in 1986. (L-R) Mr. Dallas Mackey, director of the Office of Development at the Medical Center; Mr. and Mrs. Warner Miller; and Dr. Robert Capizzi, director of the ORC. The Millers gave the money to Bowman Gray because of the kindness shown to them during their daughter’s illness and battle with cancer that eventually took her life. The Millers also lost two other family members to cancer.

1989

  • Received interim “Comprehensive” status from NCI

1990s

 

1990

  • Received NCI-designated Comprehensive Cancer Center status; one of only 24 in the nation at the time
  • Blood and Marrow Transplant (BMT) program established, second in NC

1991

  • First hyperthermic intraperitoneal chemotherapy procedure performed at Wake Forest Baptist  

1993

  • Dr. Frank M. Torti named Comprehensive Cancer Center director

Photo: Dr. Frank Torti

  • Department of Cancer Biology created at Wake Forest University Baptist Medical Center

1998

  • Breast cancer sentinel node mapping program launched

1999

  • Prostate Cancer Center of Excellence established at Wake Forest Baptist Comprehensive Cancer Center
  • NCI awarded $2 million grant to establish the Wake Forest Community Clinical Oncology Program (CCOP) Research Base
  • Elekta Gamma Knife Unit opened, becoming the first in NC and 5th in the nation

Photo: Elekta Gamma Knife unit

2000s

2000

  • Multimodality Breast Care Clinic opened

2001

  • First in the nation to perform new brain tumor treatment - placement of an intratumoral balloon delivering local radiation - the GliaSite RTS

2003

  • Brain Tumor Center of Excellence established

2004

  • Freestanding Outpatient Cancer Center building opened with new Surgical Oncology Radiation Oncology and Medical Oncology Clinics
  • Comprehensive Cancer Center awarded status as a full member of the NCI-funded New Approaches to Brain Tumor Therapy (NABTT) Central Nervous System (CNS) Consortium

2005

  • Dr. Boris Pasche named Comprehensive Cancer Center director

Photo: Dr. Boris Pasche 

2007

  • Dr. Bayard Powell presented at ASCO the incorporation of arsenic trioxide into frontline treatment of acute promyelocytic leukemia, changing treatment worldwide

2009

  • Surgical Oncology Fellowship launched

 

  • Accredited by National Accreditation Program for Breast Cancer (NAPBC)

2010s

2011

  • First patient to receive laser interstitial thermal therapy (LiTT) at Wake Forest Baptist Comprehensive Cancer Center 

2013

  • Comprehensive Cancer Center expanded inpatient cancer services with a six-floor addition 

 

2014

  • Awarded $18 million grant for NCI Community Research Program (NCORP) Research Base, one of only two cancer center-based NCORP Research Bases in the nation 
  • Office of Cancer Health Equity founded
  • Surgical oncology accreditation granted by ACGME and American Board of Surgery

2016

  • First in the nation to offer scalp cooling system to reduce hair loss in women with breast cancer (following the study that led to FDA approval)

 

2017

  • NCI funded $9.2 million P01 “Maximizing Local Access to Therapeutic Deliveries in Glioblastoma”

2019

  • One of four institutions chosen by the American Association for Cancer Research (AACR) to be part of a “dream team” of top scientists focused on finding therapies for T-cell lymphoma, a rare cancer of the blood and immune system

2020s

2020

  • CAR T-cell therapy administered to the first patient at Wake Forest Baptist Comprehensive Cancer Center
  • Wake Forest Baptist Health (including Wake Forest School of Medicine) and Atrium Health officially joined as a single enterprise

2021

  • P50 awarded to fund iDAPT center, a developing implementation science center for cancer control, only one of seven funded by NCI

2022

  • Adolescents and young adults (AYA) oncology program launched, following award from Teen Cancer America
  • Atrium Health and Advocate Aurora Health combined, creating Advocate Health
  • Atrium Health Levine Cancer Institute and Wake Forest Baptist Comprehensive Cancer Center integrate, establishing one of the largest cancer programs in the country 

2023

  • Dr. Ruben Mesa named executive diretor of the Comprehensive Cancer Center

Photo: Dr. Ruben Mesa

 

  • Cancer services at Atrium Health Levine Cancer Institute and Atrium Health Wake Forest Baptist under one name, Atrium Health Levine Cancer
  • NCI funded $9.4 million P01 Project MARVEL (Multidisciplinary Assessment of Risks from Vaping during Early Life)

2024

  • Atrium Health Levine Cancer Proton and Advanced Radiation Center (PARC) opened in Charlotte, becoming one of just 45 proton beam therapy sites in the country at the time

Comprehensive Cancer Center News


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